Shin, D., Byun, W. S., Kang, S., Kang, I., Bae, E. S., An, J. S., Im, J. H., Park, J., Kim, E., Ko, K., Hwang, S., Lee, H., Kwon, Y., Ko, Y.-J., Hong, S., Nam, S.-J., Kim, S. B., Fenical, W., Yoon, Y. J., … Oh, D.-C. (2023). Targeted and Logical Discovery of Piperazic Acid-Bearing Natural Products Based on Genomic and Spectroscopic Signatures. Journal of the American Chemical Society, 145(36), 19676–19690.
Pulat, S., Kim, D.-A., Hillman, P. F., Oh, D.-C., Kim, H., Nam, S.-J., & Fenical, W. (2023). Actinoquinazolinone, a New Quinazolinone Derivative from a Marine Bacterium Streptomyces sp. CNQ-617, Suppresses the Motility of Gastric Cancer Cells. Marine Drugs, 21(9), 489.
Pham, N. T., Alves, J., Sargison, F. A., Cullum, R., Wildenhain, J., Fenical, W., Butler, M. S., Mead, D. A., Duggan, B. M., Fitzgerald, J. R., La Clair, J. J., & Auer, M. (2023). Nanoscaled Discovery of a Shunt Rifamycin from Salinispora arenicola Using a Three-Color GFP-Tagged Staphylococcus aureus Macrophage Infection Assay. ACS Infectious Diseases, 9(8), 1499–1507.
Kim, M. C., Winter, J. M., Cullum, R., Smith, A. J., & Fenical, W. (2023). Expanding the Utility of Bioinformatic Data for the Full Stereostructural Assignments of Marinolides A and B, 24- and 26-Membered Macrolactones Produced by a Chemically Exceptional Marine-Derived Bacterium. Marine Drugs, 21(6), 367.
Pulat, S., Hillman, P. F., Kim, S., Asolkar, R. N., Kim, H., Zhou, R., Taş, İ., Gamage, C. D. B., Varlı, M., Park, S.-Y., Park, S. C., Yang, I., Shin, J., Oh, D.-C., Kim, H., Nam, S.-J., & Fenical, W. (2023). Marinobazzanan, a Bazzanane-Type Sesquiterpenoid, Suppresses the Cell Motility and Tumorigenesis in Cancer Cells. Marine Drugs, 21(3), 153.
Hillman, P. F., Lee, J. Y., Lee, J., Lee, J., Oh, D.-C., Fenical, W., & Nam, S.-J. (2023). Lodopyridones D − G from a marine-derived bacterium Saccharomonospora sp. Natural Product Research, 1–6.
Shin, Y.-H., Im, J. H., Kang, I., Kim, E., Jang, S. C., Cho, E., Shin, D., Hwang, S., Du, Y. E., Huynh, T.-H., Ko, K., Ko, Y.-J., Nam, S.-J., Awakawa, T., Lee, J., Hong, S., Abe, I., Moore, B. S., Fenical, W., … Oh, D.-C. (2023). Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams. Journal of the American Chemical Society, 145(3), 1886–1896.
Zou, W., Luo, X., Gao, M., Yu, C., Wan, X., Yu, S., Wu, Y., Wang, A., Fenical, W., Wei, Z., Zhao, Y., & Lu, Y. (2023). Optimization of cancer immunotherapy on the basis of programmed death ligand‐1 distribution and function. British Journal of Pharmacology, bph.16054.
Hirata, A. S., La Clair, J. J., Jimenez, P. C., Costa-Lotufo, L. V., & Fenical, W. (2022). Preclinical Development of Seriniquinones as Selective Dermcidin Modulators for the Treatment of Melanoma. Marine Drugs, 20(5).
Shing, B., Balen, M., Fenical, W., & Debnath, A. (2022). Development of a machine learning-based cysticidal assay and identification of an amebicidal and cysticidal marine microbial metabolite against Acanthamoeba. Microbiology Spectrum, 10.
Lee, S. E., Kim, M. J., Hillman, P. F., Oh, D. C., Fenical, W., Nam, S. J., & Lim, K. M. (2022). Deoxyvasicinone with anti-melanogenic activity from marine-derived Streptomyces sp. CNQ-617. Marine Drugs, 20(2).
Kim, S., Le, T. C., Han, S. A., Hillman, P. F., Hong, A., Hwang, S., Du, Y. E., Kim, H., Oh, D. C., Cha, S. S., Lee, J., Nam, S. J., & Fenical, W. (2022). Saccharobisindole, neoasterric methyl ester, and 7-chloro-4(1H)-quinolone: Three new compounds isolated from the marine bacterium Saccharomonospora sp. Marine Drugs, 20(1), 12.
Le, T. C., Pulat, S., Lee, J., Kim, G. J., Kim, H., Lee, E. Y., Hillman, P. F., Choi, H., Yang, I., Oh, D. C., Nam, S. J., & Fenical, W. (2022). Marine depsipeptide nobilamide i inhibits cancer cell motility and tumorigenicity via suppressing epithelial-mesenchymal transition and MMP2/9 expression. Acs Omega, 11.
Kim, M. C., Li, Z. F., Cullum, R., Molinski, T. F., Eid, M. A. G., Hebishy, A. M. S., Faraag, A. H. I., Moneim, A. E. A., Abdelfattah, M. S., & Fenical, W. (2022). Chlororesistoflavins A and B, Chlorinated Benzopyrene Antibiotics Produced by the Marine-Derived Actinomycete Streptomyces sp. Strain EG32. Journal of Natural Products, 6.
Kim, S., Hillman, P. F., Lee, J. Y., Lee, J., Lee, J., Cha, S.-S., Oh, D.-C., Nam, S.-J., & Fenical, W. (2022). Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp. The Journal of Antibiotics, 75(11), 619–625.
Castro-Falcon, G., Creamer, K. E., Chase, A. B., Kim, M. C., Sweeney, D., Glukhov, E., Fenical, W., & Jensen, P. R. (2022). Structure and candidate biosynthetic gene cluster of a manumycin-type metabolite from Salinispora pacifica. Journal of Natural Products, 85(4), 980–986. ://WOS:000791431400023
Hirata, A. S., Rezende-Teixeira, P., Machado-Neto, J. A., Jimenez, P. C., Clair, J. J. L., Fenical, W., & Costa-Lotufo, L. V. (2021). Seriniquinones as therapeutic leads for treatment of BRAF and NRAS mutant melanomas. Molecules, 26(23), 15.
Kim, M. C., Winter, J. M., Asolkar, R. N., Boonlarppradab, C., Cullum, R., & Fenical, W. (2021). Marinoterpins A-C: Rare linear merosesterterpenoids from marine-derived actinomycete bacteria of the family Streptomycetaceae. Journal of Organic Chemistry, 86(16), 11140–11148.
Kim, S., Lee, C. W., Park, S. Y., Asolkar, R. N., Kim, H., Kim, G. J., Oh, S. J., Kim, Y., Lee, E. Y., Oh, D. C., Yang, I., Paik, M. J., Choi, H., Nam, S. J., & Fenical, W. (2021). Acremonamide, a cyclic pentadepsipeptide with wound-healing properties isolated from a marine-derived fungus of the genus Acremonium. Journal of Natural Products, 84(8), 2249–2255.
Purdy, T. N., Kim, M. C., Cullum, R., Fenical, W., & Moore, B. S. (2021). Discovery and biosynthesis of tetrachlorizine reveals enzymatic benzylic dehydrogenation via an ortho-quinone methide. Journal of the American Chemical Society, 143(10), 3682–3686.
Taylor, P., Shyong, Y. J., Samskey, N., Ho, K. Y., Radic, Z., Fenical, W., Sharpless, K. B., Kovarik, Z., & Camacho-Hernandez, G. A. (2021). Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical. Journal of Neurochemistry.
Nair, V., Kim, M. C., Golen, J. A., Rheingold, A. L., Castro, G. A., Jensen, P. R., & Fenical, W. (2020). Verrucosamide, a cytotoxic 1,4-thiazepane-containing thiodepsipeptide from a marine-derived actinomycete. Marine Drugs, 18(11).
Lee, J., Gamage, C. D. B., Kim, G. J., Hillman, P. F., Lee, C., Lee, E. Y., Choi, H., Kim, H., Nam, S. J., & Fenical, W. (2020). Androsamide, a cyclic tetrapeptide from a marine Nocardiopsis sp., suppresses motility of colorectal cancer cells. Journal of Natural Products, 83(10), 3166–3172.
Kim, M. C., Winter, J. M., Cullum, R., Li, Z. F., & Fenical, W. (2020). Complementary genomic, bioinformatics, and chemical approaches facilitate the absolute structure assignment of lonostatin, a linear polyketide from a rare marine-derived actinomycete. Acs Chemical Biology, 15(9), 2507–2515.
da Silva, R. M., Carrao, D. B., Habenschus, M. D., Jimenez, P. C., Lops, N. P., Fenical, W., Costa-Lotufo, L. V., & de Oliveira, A. R. M. (2020). Prediction of seriniquinone-drug interactions by in vitro inhibition of human cytochrome P450 enzymes. Toxicology in Vitro, 65.
Kim, M. C., Cullum, R., Hebishy, A. M. S., Mohamed, H. A., Faraag, A. H. I., Salah, N. M., Abdelfattah, M. S., & Fenical, W. (2020). Mersaquinone, a new tetracene derivative from the marine-derived Streptomyces sp. EG1 exhibiting activity against Methicillin-Resistant Staphylococcus aureus (MRSA). Antibiotics-Basel, 9(5).
Bai, R., Cruz-Monserrate, Z., Fenical, W., Pettit, G. R., & Hamel, E. (2020). Interaction of diazonamide A with tubulin. Archives of Biochemistry and Biophysics, 680.
Duggan, B. M., Cullum, R., Fenical, W., Amador, L. A., Rodriguez, A. D., & La Clair, J. J. (2019). Searching for small molecules with an atomic sort. Angewandte Chemie-International Edition.
Kim, M. C., Cullum, R., Machado, H., Smith, A. J., Yang, I., Rodvold, J. J., & Fenical, W. (2019). Photopiperazines A-D, photosensitive interconverting diketopiperazines with significant and selective activity against U87 glioblastoma cells, from a rare, marine-derived actinomycete of the family Streptomycetaceae. Journal of Natural Products, 82(8), 2262–2267.
Ryu, M. J., Hwang, S., Kim, S., Yang, I., Oh, D. C., Nam, S. J., & Fenical, W. (2019). Meroindenon and merochlorins E and F, antibacterial meroterpenoids from a marine-derived sediment bacterium of the genus Streptomyces. Organic Letters, 21(15), 5779–5783.
Zhou, X. F., Liang, Z., Li, K. L., Fang, W., Tian, Y. X., Luo, X. W., Chen, Y. L., Zhan, Z. K., Zhang, T., Liao, S. R., Liu, S. W., Liu, Y. H., Fenical, W., & Tang, L. (2019). Exploring the natural piericidins as anti-renal cell carcinoma agents targeting peroxiredoxin 1. Journal of Medicinal Chemistry, 62(15), 7058–7069.
Shang, Z., Winter, J. M., Kauffman, C. A., Yang, I., & Fenical, W. (2019). Salinipeptins: Integrated genomic and chemical approaches reveal unusual D-amino acid-containing ribosomally synthesized and post-translationally modified peptides (RiPPs) from a Great Salt Lake Streptomyces sp. Acs Chemical Biology, 14(3), 415–425.
Le, T. C., Lee, E. J., Lee, J., Hong, A., Yim, C. Y., Yang, I., Choi, H., Chin, J., Cho, S. J., Ko, J., Hwang, H., Nam, S. J., & Fenical, W. (2019). Saccharoquinoline, a cytotoxic alkaloidal meroterpenoid from marine-derived bacterium Saccharomonospora sp. Marine Drugs, 17(2).
Hammons, J. C., Trzoss, L., Jimenez, P. C., Hirata, A. S., Costa-Lotufo, L. V., La Clair, J. J., & Fenical, W. (2019). Advance of seriniquinone analogues as melanoma agents. Acs Medicinal Chemistry Letters, 10(2), 186–190.
Kim, M. C., Machado, H., Jang, K. H., Trzoss, L., Jensen, P. R., & Fenical, W. (2018). Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora. Journal of the American Chemical Society, 140(34), 10775–10784.
Leutou, A. S., Yang, I. H., Le, T. C., Hahn, D., Lim, K. M., Nam, S. J., & Fenical, W. (2018). Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis. Journal of Antibiotics, 71(6), 609–612.
Zheng, J., McKinnie, S. M. K., El Gama, A., Fengit, W., Dong, Y., Agarwal, V., Fenical, W., Kumar, A., Cao, Z. Y., Moore, B. S., & Pessah, I. N. (2018). Organohalogens naturally biosynthesized in marine environments and produced as disinfection byproducts alter sarco/endoplasmic reticulum ca2+ dynamics. Environmental Science & Technology, 52(9), 5469–5478.
da Silva, R. M., Guaratini, T., Jimenez, P. C., Fenical, W., Costa-Lotufo, L. V., Vessecchi, R., & Lopes, N. P. (2018). Mass spectrometry analysis of protonated marine natural product seriniquinone. Journal of the Brazilian Chemical Society, 29(5), 1162–1166.
Nakatsuji, T., Chen, T. H., Butcher, A. M., Trzoss, L. L., Nam, S. J., Shirakawa, K. T., Zhou, W., Oh, J., Otto, M., Fenical, W., & Gallo, R. L. (2018). A commensal strain of Staphylococcus epidermidis protects against skin neoplasia. Science Advances, 4(2).
Amos, G. C. A., Awakawa, T., Tuttle, R. N., Letzel, A. C., Kim, M. C., Kudo, Y., Fenical, W., Moore, B. S., & Jensen, P. R. (2017). Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality. Proceedings of the National Academy of Sciences of the United States of America, 114(52), E11121–E11130.
Yim, C. Y., Le, T. C., Lee, T. G., Yang, I., Choi, H., Lee, J., Kang, K. Y., Lee, J. S., Lim, K. M., Yee, S. T., Kang, H., Nam, S. J., & Fenical, W. (2017). Saccharomonopyrones A-C, New alpha-Pyrones from a Marine Sediment-Derived Bacterium Saccharomonospora sp CNQ-490. Marine Drugs, 15(8).
Le, T. C., Yim, C. Y., Park, S., Katila, N., Yang, I., Song, M. C., Yoon, Y. J., Choi, D. Y., Choi, H., Nam, S. J., & Fenical, W. (2017). Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp. Bioorganic & Medicinal Chemistry Letters, 27(14), 3123–3126.
Yang, I., Yoon, J., Kim, D., Hahn, D., Nam, S. J., & Fenical, W. (2017). 4Z- and 4E-12-deoxydihydrokromycins, two naturally occurring kromycin aglycones of pikromycin from Streptomyces sp. Tetrahedron Letters, 58(24), 2322–2324.
Asolkar, R. N., Singh, A., Jensen, P. R., Aalbersberg, W., Carte, B. K., Feussner, K. D., Subramani, R., DiPasquale, A., Rheingold, A. L., & Fenical, W. (2017). Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete Glade MAR4. Tetrahedron, 73(16), 2234–2241.
Lee, H. W., Choi, H., Nam, S. J., Fenical, W., & Kim, H. (2017). Potent Inhibition of Monoamine Oxidase B by a Piloquinone from Marine-Derived Streptomyces sp CNQ-027. Journal of Microbiology and Biotechnology, 27(4), 785–790.
Kumar, A., Borgen, M., Aluwihare, L. I., & Fenical, W. (2017). Ozone-activated halogenation of mono- and dimethylbipyrrole in seawater. Environmental Science & Technology, 51(1), 589–595.
Hay, A. J., Yang, M. H., Xia, X. Y., Liu, Z., Hammons, J., Fenical, W., & Zhu, J. (2017). Calcium enhances bile salt-dependent virulence activation in Vibrio cholerae. Infection and Immunity, 85(1).
Beuzer, P., Axelrod, J., Trzoss, L., Fenical, W., Dasari, R., Evidente, A., Kornienko, A., Cang, H., & La Clair, J. J. (2016). Single dish gradient screening of small molecule localization. Organic & Biomolecular Chemistry, 14(35), 8241–8245.
Zhou, X. F., & Fenical, W. (2016). The unique chemistry and biology of the piericidins. Journal of Antibiotics, 69(8), 582–593.
La Clair, J. J., Fenical, W., & Costa-Lotufo, L. V. (2016). Elucidating the mode of action of marine natural products through an immunoaffinity fluorescent (iaf) approach. Journal of the Brazilian Chemical Society, 27(8), 1346–1354.