William Fenical

WILLIAM FENICAL

Emeritus

Marine Biology, Marine Chemistry and Geochemistry

CTR FOR MARINE BIOTEC & BIOMED

Distinguished Professor of Oceanography

Research Interests

Chemistry of marine plants, microorganisms and invertebrate animals.
Utilization of marine-derived compounds for the treatment of various human diseases, in particular cancer and infectious diseases.

Degrees

B.S., California State Polytechnic University
M.S., San Jose State University
PhD, University of California, Riverside

Recent Publications

9129767 PJFFIS8I 1 apa 5 date desc Fenical, W. 265 https://wfenical.scrippsprofiles.ucsd.edu/wp-content/plugins/zotpress/

%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%2222PTPG5I%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Holland%20et%20al.%22%2C%22parsedDate%22%3A%222025-06-13%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHolland%2C%20D.%20C.%2C%20Iizumi%2C%20R.%2C%20Shende%2C%20V.%20V.%2C%20%26amp%3B%20%26lt%3Bstrong%26gt%3BFenical%2C%20W.%26lt%3B%5C%2Fstrong%26gt%3B%20%282025%29.%20Isolation%20of%20Verrucosins%20A%26%23x2013%3BE%20from%20a%20Marine%20%26lt%3Bi%26gt%3BVerrucosispora%26lt%3B%5C%2Fi%26gt%3B%20sp.%20Reveals%20a%20Unifying%20Biosynthetic%20Hypothesis%20for%20Linear%20and%20Macrocyclic%20Polyketides.%20%26lt%3Bi%26gt%3BJournal%20of%20Natural%20Products%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.jnatprod.5c00373%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.jnatprod.5c00373%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Isolation%20of%20Verrucosins%20A%5Cu2013E%20from%20a%20Marine%20%3Ci%3EVerrucosispora%3C%5C%2Fi%3E%20sp.%20Reveals%20a%20Unifying%20Biosynthetic%20Hypothesis%20for%20Linear%20and%20Macrocyclic%20Polyketides%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Darren%20C.%22%2C%22lastName%22%3A%22Holland%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Reiko%22%2C%22lastName%22%3A%22Iizumi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vikram%20V.%22%2C%22lastName%22%3A%22Shende%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Fenical%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-06-13%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1021%5C%2Facs.jnatprod.5c00373%22%2C%22ISSN%22%3A%220163-3864%2C%201520-6025%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubs.acs.org%5C%2Fdoi%5C%2F10.1021%5C%2Facs.jnatprod.5c00373%22%2C%22collections%22%3A%5B%22PJFFIS8I%22%5D%2C%22dateModified%22%3A%222025-07-11T16%3A12%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22IA74RSKZ%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bring%20Horvath%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-08%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBring%20Horvath%2C%20E.%20R.%2C%20Brazelton%2C%20W.%20J.%2C%20Kim%2C%20M.%20C.%2C%20Cullum%2C%20R.%2C%20Mulvey%2C%20M.%20A.%2C%20%26lt%3Bstrong%26gt%3BFenical%2C%20W.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20%26amp%3B%20Winter%2C%20J.%20M.%20%282024%29.%20Bacterial%20diversity%20and%20chemical%20ecology%20of%20natural%20product%26%23x2013%3Bproducing%20bacteria%20from%20Great%20Salt%20Lake%20sediment.%20%26lt%3Bi%26gt%3BISME%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B4%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20ycae029.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fismeco%5C%2Fycae029%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fismeco%5C%2Fycae029%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Bacterial%20diversity%20and%20chemical%20ecology%20of%20natural%20product%5Cu2013producing%20bacteria%20from%20Great%20Salt%20Lake%20sediment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elijah%20R%22%2C%22lastName%22%3A%22Bring%20Horvath%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20J%22%2C%22lastName%22%3A%22Brazelton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Min%20Cheol%22%2C%22lastName%22%3A%22Kim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Reiko%22%2C%22lastName%22%3A%22Cullum%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthew%20A%22%2C%22lastName%22%3A%22Mulvey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Fenical%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jaclyn%20M%22%2C%22lastName%22%3A%22Winter%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Great%20Salt%20Lake%20%28GSL%29%2C%20located%20northwest%20of%20Salt%20Lake%20City%2C%20UT%2C%20is%20the%20largest%20terminal%20lake%20in%20the%20USA.%20While%20the%20average%20salinity%20of%20seawater%20is%20~3.3%25%2C%20the%20salinity%20in%20GSL%20ranges%20between%205%25%20and%2028%25.%20In%20addition%20to%20being%20a%20hypersaline%20environment%2C%20GSL%20also%20contains%20toxic%20concentrations%20of%20heavy%20metals%2C%20such%20as%20arsenic%2C%20mercury%2C%20and%20lead.%20The%20extreme%20environment%20of%20GSL%20makes%20it%20an%20intriguing%20subject%20of%20study%2C%20both%20for%20its%20unique%20microbiome%20and%20its%20potential%20to%20harbor%20novel%20natural%20product%5Cu2013producing%20bacteria%2C%20which%20could%20be%20used%20as%20resources%20for%20the%20discovery%20of%20biologically%20active%20compounds.%20Though%20work%20has%20been%20done%20to%20survey%20and%20catalog%20bacteria%20found%20in%20GSL%2C%20the%20Lake%5Cu2019s%20microbiome%20is%20largely%20unexplored%2C%20and%20little%20to%20no%20work%20has%20been%20done%20to%20characterize%20the%20natural%20product%20potential%20of%20GSL%20microbes.%20Here%2C%20we%20investigate%20the%20bacterial%20diversity%20of%20two%20important%20regions%20within%20GSL%2C%20describe%20the%20first%20genomic%20characterization%20of%20Actinomycetota%20isolated%20from%20GSL%20sediment%2C%20including%20the%20identification%20of%20two%20new%20Actinomycetota%20species%2C%20and%20provide%20the%20first%20survey%20of%20the%20natural%20product%20potential%20of%20GSL%20bacteria.%22%2C%22date%22%3A%222024-01-08%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1093%5C%2Fismeco%5C%2Fycae029%22%2C%22ISSN%22%3A%222730-6151%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facademic.oup.com%5C%2Fismecommun%5C%2Farticle%5C%2Fdoi%5C%2F10.1093%5C%2Fismeco%5C%2Fycae029%5C%2F7619006%22%2C%22collections%22%3A%5B%22PJFFIS8I%22%5D%2C%22dateModified%22%3A%222024-04-11T23%3A15%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22HGPJ3IFQ%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Miguel%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMiguel%2C%20R.%20D.%20A.%2C%20Hirata%2C%20A.%20S.%2C%20Salata%2C%20G.%20C.%2C%20Apolin%26%23xE1%3Brio%2C%20A.%20C.%2C%20Barroso%2C%20V.%20M.%2C%20Ishida%2C%20K.%2C%20La%20Clair%2C%20J.%20J.%2C%20%26lt%3Bstrong%26gt%3BFenical%2C%20W.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Martins%2C%20T.%20S.%2C%20Costa-Lotufo%2C%20L.%20V.%2C%20%26amp%3B%20Lopes%2C%20L.%20B.%20%282024%29.%20Topical%20delivery%20of%20seriniquinone%20for%20treatment%20of%20skin%20cancer%20and%20fungal%20infections%20is%20enabled%20by%20a%20liquid%20crystalline%20lamellar%20phase.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Pharmaceutical%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B192%26lt%3B%5C%2Fi%26gt%3B%2C%20106635.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejps.2023.106635%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejps.2023.106635%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Topical%20delivery%20of%20seriniquinone%20for%20treatment%20of%20skin%20cancer%20and%20fungal%20infections%20is%20enabled%20by%20a%20liquid%20crystalline%20lamellar%20phase%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rodrigo%20Dos%20A.%22%2C%22lastName%22%3A%22Miguel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Amanda%20S.%22%2C%22lastName%22%3A%22Hirata%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giovanna%20C.%22%2C%22lastName%22%3A%22Salata%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexsandra%20C.%22%2C%22lastName%22%3A%22Apolin%5Cu00e1rio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vinicius%20M.%22%2C%22lastName%22%3A%22Barroso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kelly%22%2C%22lastName%22%3A%22Ishida%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20J.%22%2C%22lastName%22%3A%22La%20Clair%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Fenical%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tereza%20S.%22%2C%22lastName%22%3A%22Martins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leticia%20V.%22%2C%22lastName%22%3A%22Costa-Lotufo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luciana%20B.%22%2C%22lastName%22%3A%22Lopes%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2201%5C%2F2024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ejps.2023.106635%22%2C%22ISSN%22%3A%2209280987%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS0928098723002658%22%2C%22collections%22%3A%5B%22PJFFIS8I%22%5D%2C%22dateModified%22%3A%222024-02-14T20%3A04%3A23Z%22%7D%7D%2C%7B%22key%22%3A%22II958C66%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Yuan%20et%20al.%22%2C%22parsedDate%22%3A%222023-12-08%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BYuan%2C%20A.%2C%20Fong%2C%20H.%2C%20Nguyen%2C%20J.%20V.%2C%20Nguyen%2C%20S.%2C%20Norman%2C%20P.%2C%20Cullum%2C%20R.%2C%20%26lt%3Bstrong%26gt%3BFenical%2C%20W.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20%26amp%3B%20Debnath%2C%20A.%20%282023%29.%20High-Throughput%20Screen%20of%20Microbial%20Metabolites%20Identifies%20F%20%26lt%3Bsub%26gt%3B1%26lt%3B%5C%2Fsub%26gt%3B%20F%20%26lt%3Bsub%26gt%3BO%26lt%3B%5C%2Fsub%26gt%3B%20ATP%20Synthase%20Inhibitors%20as%20New%20Leads%20for%20%26lt%3Bi%26gt%3BNaegleria%20fowleri%26lt%3B%5C%2Fi%26gt%3B%20Infection.%20%26lt%3Bi%26gt%3BACS%20Infectious%20Diseases%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B9%26lt%3B%5C%2Fi%26gt%3B%2812%29%2C%202622%26%23x2013%3B2631.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facsinfecdis.3c00437%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facsinfecdis.3c00437%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22High-Throughput%20Screen%20of%20Microbial%20Metabolites%20Identifies%20F%20%3Csub%3E1%3C%5C%2Fsub%3E%20F%20%3Csub%3EO%3C%5C%2Fsub%3E%20ATP%20Synthase%20Inhibitors%20as%20New%20Leads%20for%20%3Ci%3ENaegleria%20fowleri%3C%5C%2Fi%3E%20Infection%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alice%22%2C%22lastName%22%3A%22Yuan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hayley%22%2C%22lastName%22%3A%22Fong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jennifer%20V.%22%2C%22lastName%22%3A%22Nguyen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sophia%22%2C%22lastName%22%3A%22Nguyen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Payton%22%2C%22lastName%22%3A%22Norman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Reiko%22%2C%22lastName%22%3A%22Cullum%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Fenical%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anjan%22%2C%22lastName%22%3A%22Debnath%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-12-08%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1021%5C%2Facsinfecdis.3c00437%22%2C%22ISSN%22%3A%222373-8227%2C%202373-8227%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubs.acs.org%5C%2Fdoi%5C%2F10.1021%5C%2Facsinfecdis.3c00437%22%2C%22collections%22%3A%5B%22PJFFIS8I%22%5D%2C%22dateModified%22%3A%222024-02-14T18%3A11%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22EB2FQ6SP%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Shin%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-13%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BShin%2C%20D.%2C%20Byun%2C%20W.%20S.%2C%20Kang%2C%20S.%2C%20Kang%2C%20I.%2C%20Bae%2C%20E.%20S.%2C%20An%2C%20J.%20S.%2C%20Im%2C%20J.%20H.%2C%20Park%2C%20J.%2C%20Kim%2C%20E.%2C%20Ko%2C%20K.%2C%20Hwang%2C%20S.%2C%20Lee%2C%20H.%2C%20Kwon%2C%20Y.%2C%20Ko%2C%20Y.-J.%2C%20Hong%2C%20S.%2C%20Nam%2C%20S.-J.%2C%20Kim%2C%20S.%20B.%2C%20%26lt%3Bstrong%26gt%3BFenical%2C%20W.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Yoon%2C%20Y.%20J.%2C%20%26%23x2026%3B%20Oh%2C%20D.-C.%20%282023%29.%20Targeted%20and%20Logical%20Discovery%20of%20Piperazic%20Acid-Bearing%20Natural%20Products%20Based%20on%20Genomic%20and%20Spectroscopic%20Signatures.%20%26lt%3Bi%26gt%3BJournal%20of%20the%20American%20Chemical%20Society%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B145%26lt%3B%5C%2Fi%26gt%3B%2836%29%2C%2019676%26%23x2013%3B19690.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Fjacs.3c04699%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Fjacs.3c04699%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Targeted%20and%20Logical%20Discovery%20of%20Piperazic%20Acid-Bearing%20Natural%20Products%20Based%20on%20Genomic%20and%20Spectroscopic%20Signatures%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Shin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Woong%20Sub%22%2C%22lastName%22%3A%22Byun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sangwook%22%2C%22lastName%22%3A%22Kang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ilnam%22%2C%22lastName%22%3A%22Kang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eun%20Seo%22%2C%22lastName%22%3A%22Bae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joon%20Soo%22%2C%22lastName%22%3A%22An%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ji%20Hyeon%22%2C%22lastName%22%3A%22Im%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jiyoon%22%2C%22lastName%22%3A%22Park%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eunji%22%2C%22lastName%22%3A%22Kim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Keebeom%22%2C%22lastName%22%3A%22Ko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sunghoon%22%2C%22lastName%22%3A%22Hwang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Honghui%22%2C%22lastName%22%3A%22Lee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yun%22%2C%22lastName%22%3A%22Kwon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon-Joo%22%2C%22lastName%22%3A%22Ko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suckchang%22%2C%22lastName%22%3A%22Hong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sang-Jip%22%2C%22lastName%22%3A%22Nam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Seung%20Bum%22%2C%22lastName%22%3A%22Kim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Fenical%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yeo%20Joon%22%2C%22lastName%22%3A%22Yoon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jang-Cheon%22%2C%22lastName%22%3A%22Cho%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sang%20Kook%22%2C%22lastName%22%3A%22Lee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dong-Chan%22%2C%22lastName%22%3A%22Oh%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-09-13%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1021%5C%2Fjacs.3c04699%22%2C%22ISSN%22%3A%220002-7863%2C%201520-5126%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubs.acs.org%5C%2Fdoi%5C%2F10.1021%5C%2Fjacs.3c04699%22%2C%22collections%22%3A%5B%22PJFFIS8I%22%5D%2C%22dateModified%22%3A%222023-10-25T17%3A19%3A52Z%22%7D%7D%5D%7D

Holland, D. C., Iizumi, R., Shende, V. V., & Fenical, W. (2025). Isolation of Verrucosins A–E from a Marine Verrucosispora sp. Reveals a Unifying Biosynthetic Hypothesis for Linear and Macrocyclic Polyketides. Journal of Natural Products. https://doi.org/10.1021/acs.jnatprod.5c00373

Bring Horvath, E. R., Brazelton, W. J., Kim, M. C., Cullum, R., Mulvey, M. A., Fenical, W., & Winter, J. M. (2024). Bacterial diversity and chemical ecology of natural product–producing bacteria from Great Salt Lake sediment. ISME Communications, 4(1), ycae029. https://doi.org/10.1093/ismeco/ycae029

Miguel, R. D. A., Hirata, A. S., Salata, G. C., Apolinário, A. C., Barroso, V. M., Ishida, K., La Clair, J. J., Fenical, W., Martins, T. S., Costa-Lotufo, L. V., & Lopes, L. B. (2024). Topical delivery of seriniquinone for treatment of skin cancer and fungal infections is enabled by a liquid crystalline lamellar phase. European Journal of Pharmaceutical Sciences, 192, 106635. https://doi.org/10.1016/j.ejps.2023.106635

Yuan, A., Fong, H., Nguyen, J. V., Nguyen, S., Norman, P., Cullum, R., Fenical, W., & Debnath, A. (2023). High-Throughput Screen of Microbial Metabolites Identifies F ₁ F _O ATP Synthase Inhibitors as New Leads for Naegleria fowleri Infection. ACS Infectious Diseases, 9(12), 2622–2631. https://doi.org/10.1021/acsinfecdis.3c00437

Shin, D., Byun, W. S., Kang, S., Kang, I., Bae, E. S., An, J. S., Im, J. H., Park, J., Kim, E., Ko, K., Hwang, S., Lee, H., Kwon, Y., Ko, Y.-J., Hong, S., Nam, S.-J., Kim, S. B., Fenical, W., Yoon, Y. J., … Oh, D.-C. (2023). Targeted and Logical Discovery of Piperazic Acid-Bearing Natural Products Based on Genomic and Spectroscopic Signatures. Journal of the American Chemical Society, 145(36), 19676–19690. https://doi.org/10.1021/jacs.3c04699